Self-regulating drug delivery

Developing a self-regulating control system for intravenous drug administration -- using aminoglycosides as an example

Summary

Our goal is to put together a sensor-pump system which would be able to adjust drug output of aminoglycosides based on real time sensing of drug in plasma. This would involve several stages, the first being the development of a functional sensor over the appropriate therapeutic range of concentrations. Similarly, a device will be designed which can attach to current hospital drip bags to control output and have configurable parameters for information such as normal drug clearance, volume of distribution, concentration of drug being delivered, and so on. The software to calculate the appropriate output will also be written.

Hackster Project Documentation

The Team

Palaniappan Ganesh Nagappan, Physiology Department, Emmanuel College, Cambridge
Primarily contribute to the design and programming of the pump and help with the development of the sensor.

David Chong Tian Wei, Genetics Department, St Edmund’s College, Cambridge
Primarily contribute to the design and programming of the pump and help with the development of the sensor.