A complete listing of open projects funded by the Synthetic Biology Strategic Research Initiative at the University of Cambridge, the OpenPlant Synthetic Biology Research Centre and the Biomaker Challenge.

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Biomaker Challenge Projects

Winter 2018-2019

  1. A XOD node for the Bosch BNO055 9-axis absolute orientation sensor

  2. Simple GPS modules

  3. Automating the output of genetic circuits using light adjustable promoter systems

  4. Nodes for accessible urban farming science: easy study of plant growth in limited spaces

  5. Aquaneers: a full suite of monitoring sensors and actuation tools for aquariums

  6. Fully automated optimal home grow chamber

  7. Ultrasonic hydrometer for remote monitoring of beer fermentation

  8. Facile optical measurement of real time liquid microbial growth

  9. Menu-driven user-interface construction tool for XOD

Summer 2018

  1. Temperature controlled container for sample transportation

  2. Automated water irrigation, lighting and monitoring system for plant growth

  3. Agarose device to generate and study an in vitro embryonic model system

  4. Wearable biosensor for monitoring vaginal discharge

  5. Evolution under temporally-controlled selection: The Oscillostat

  6. Open bioreactor for local enzyme manufacturing

  7. Visual Programming for Biomakers

  8. Improving dual-view imaging in a custom-built light sheet microscope

  9. Spectre - Palm-sized Spectrophotometer

  10. LyseeFlask

Summer 2017

  1. A cell-free sensor platform for the quantification of arsenic concentrations in drinking water

  2. A Device for Real-Time Monitoring of Protein Synthesis

  3. A low cost reusable microfluidic device for the detection of antibiotic  resistant genes in bacteria isolated from patient samples

  4. A low cost, point-of- care device to measure blood haemoglobin  levels, using calorimetry and infrared spectroscopy

  5. A low-cost colorimeter for accurate detection of colour changes in medical diagnostic tests

  6. A low-cost, pressurized liquid chromatography system for protein  purification

  7. An accessible, low cost, hand-held device for detecting counterfeit antimalarial drugs, using quartz crystal microbalance technology

  8. A microdroplet incubator to establish 3D organoids cultures from oesophageal  adenocarcinoma

  9. A sensor to improve the accuracy of stereotactic brain biopsies for the  diagnosis of brain tumours

  10. An artificial habitat to investigate  Boquila trifoliata mimicry

  11. Cheap Do-It- Yourself Small Volume UV Spectrometer for  Nucleic Acid and Protein Quantitation

  12. Detecting alterations in ionic concentrations associated with  different cellular states

  13. Detecting pathogens in sewage sludge

  14. Developing a self-regulating control system for intravenous drug  administration -- using aminoglycosides as an example

  15. Development of an anti-TFF3 functionalized surface to capture of Barrett’s oesophagus cells

  16. DIY bioacoustics

  17. Field portable colorimeter

  18. Functional membrane-based integrated biosensing devices for detection and  quantitation of specific nucleic acids and other biomolecules

  19. Handheld syringe pump with heating element

  20. KNOW-FLOW/ A low-cost programmable blood flow system

  21. Low Cost Wearable Sensors Strain Sensors for illness  identification via Gait, Posture and muscle usage

  22. Low-Cost Multispectral Imagery for UAV-based Vegetation Monitoring

  23. Macrophotography of fern gametophytes using a DIY focus stacking system

  24. Microfluidic Turntable for molecular  diagnostic testing

  25. OptoFlow/ Optical flow rate measurement for microfluidics

  26. Puzzle-solving Bacterial Pet/ Imaging Platform for Microfluidics-based Reinforced Learning with  Motile Bacterial Cells

  27. Remote Environment Controller for  Experiments in Extreme Environments

  28. Sci-Fi Cam

  29. Ultrasonic Plant Height System for High-Throughput Plant Phenotyping

  30. Real-Time monitoring of cell proliferation

  31. A light intensity meter to measure plant growth conditions

  32. The Charge on Cancer: Using Induced Dipole Moment to Electrostatically Separate Healthy and Cancer Cell-Metal Nanoparticle Complex

  33. Automatic size and weight measurements of fish

  34. Building DeepSkin: a low-cost state-of-the-art digital dermatoscope

  35. PiRMA: A low-cost rodent physiology monitoring bed for pre-clinical experiments

  36. Using stem cells to sense and report developmental signalling gradients: towards advanced spatial in vitro models of embryogenesis

  37. Improving Open Source Motion Control With Arduino

  38. A Place in the Sun: Creating bespoke spectral recipes using a simple LED Array

  39. An open source electro-pneumatic controller for integrated microfluidic chips

  40. iLAB: next-generation coding for physiological monitoring

  41. Open-source Lasercut Portable Incubator for Microbiology

OpenPlant Fund Projects

July 2018 (projects 62-71)

December 2017 (projects 52-61)

July 2017 (projects 41-51)

December 2016 (projects 31-40)

January 2016 (projects 17-30)

July 2015 (projects 1-16)

SynBio Fund Projects

November 2015 (projects 10-21)

  • SynBio Student Society

  • SynBioHub: Patent information system for synthetic biology

  • Synthesis of novel optimised lux reporters for eukaryotic systems

  • CamOptimus: Self-contained user-friendly multi-parameter optimisation platform for non-specialist experimental biologists

  • Reliable IP-free system for inter-chassis transfer of the high molecular weight DNA

  • A piezoelectric bio-platform to image and stimulate cellular interactions

  • Interactive web-based software tool for biological circuit design (Extension plan)

  • Development of a microfluidic device for high-throughput analysis of genetic circuits in plant protoplasts.

  • Bio-Hackathon

  • Low cost solution for high throughput bacterial electrotransformation

  • CELLUWIN: 3D printing for cellulose

  • Organotypic cultures as tools for functional screening of drugs to promote oligodendrocyte differentiation and CNS myelination.

March 2015 (projects 1-9)

  • Engineering of self­ cloning brewer’s yeast for novel terpene profiles in beer.  

  • 3D printed microscope

  • Interactive web­ based software for genetic circuit design

  • Novel bioluminescent reporters

  • DIY Biolab 

  • Flexible, low cost, live­ cell imaging platform

  • Faster engineering of cyanobacteria

  • Finding new recombinases

  • The Green Mother Machine: A microfluidics device for cyanobacteria